Oncological Surgery

Surgery is the treatment of choice for most solid tumors. Complete removal of the tumor is the aim. It provides the best prognosis and reduces the need for additional therapy. Unfortunately, the hands, eyes and experience of a surgeon often do not suffice to achieve this result.



RiverD is developing the MarginGuide-system. This dedicated Raman spectroscopic device is intended for assessment of tumor resection margins on the resected tissue.

It employs a thin fiber-optic needle to measure the distance between a resection surface and the tumor. This takes only a few seconds, which enables a thorough examination of all resection surfaces, while the patient is still in the operating room.

The MarginGuide system reports the locations of incomplete tumor resection, providing the surgeon with the option to remove additional tissue in order to achieve a complete resection.

Oral Cavity Cancer

Validation studies are currently underway for application in oral cavity cancer surgery, which is unfortunately notorious for a very low percentage of complete tumor resections.

We expect the MarginGuide will be equally valuable to improve surgical treatment procedures in other forms of cancer.


Supported by the European Union’s Eurostars 2 programme