Taking the guesswork out of quantifying in vivo skin penetration: A method to directly measure dynamic in vivo penetration of topical substances using confocal Raman spectroscopy.

The technique has been automated in RiverD's latest analysis software SkinTools 3.

Peter J. Caspers, Claudio Nico, Tom C. Bakker Schut, Johanna de Sterke, Paul D. A. Pudney, Patricia R. Curto, Abigail Illand, Gerwin J. Puppels, "Method to quantify the in vivo skin penetration of topically applied materials based on confocal Raman spectroscopy,"

Translational Biophotonics 


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